Cannabinoid

Synthetic cannabinoids encompass a variety of distinct chemical classes: the classical cannabinoids structurally related to THC, the nonclassical cannabinoids (cannabimimetics) including the aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and arylsulphonamides, as well as eicosanoids related to the endocannabinoids.[2] Cannabinoid receptors[edit] Cannabinoid receptor type 1[edit] CB1 receptors are found primarily in the brain, more specifically in the basal ganglia and in the limbic system, including the hippocampus.[1] They are also found in the cerebellum and in both male and female reproductive systems. CB1 receptors are absent in the medulla oblongata, the part of the brain stem responsible for respiratory and cardiovascular functions. Thus, there is not the risk of respiratory or cardiovascular failure that can be produced by some drugs. Cannabinoid receptor type 2[edit] Phytocannabinoids[edit] Cannabis-derived cannabinoids[edit] Types[edit] Tetrahydrocannabinol[edit] Cannabinol[edit]

Cannabis Etymology The word cannabis is from Greek κάνναβις (kánnabis) (see Latin cannabis),[4] which was originally Scythian or Thracian.[5] It is related to the Persian kanab, the English canvas and possibly even to the English hemp (Old English hænep).[5] In modern Hebrew, קַנַּבּוֹס qannabōs modern pronunciation: [kanaˈbos] is used but מַעֲלֶה עָשָׁן maʿăleh ʿāšān modern pronunciation: [ma.aˈle aˈʃan] (smoke bringer) is the ancient term. Old Akkadian qunnabtu, Neo-Assyrian and Neo-Babylonian qunnabu were used to refer to the plant meaning "a way to produce smoke."[6][7][8] Description Cannabis is an annual, dioecious, flowering herb. The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a Cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). Micrograph sativa (left), indica (right) Taxonomy Top of Cannabis plant in vegetative growth stage Early classifications 20th century

Marijuana (Weed) History and Facts People around the world have been smoking marijuana for thousands of years while also using the hemp plant for everything from fabric and rope to ethanol fuel. Unfortunately, somewhere along the way, a man with a bit of power and enough determination decided pot was wicked, evil and narcotic. He moved mountains to make it illegal worldwide. Between 1937 and 1947, the government spent $220 million on the war against drugs. First Fabric Known to Man The hemp plant, also called cannabis or marijuana, has been used around the world for thousands of years. Cannabis Seeds Used as Food Around 6000 BCE hemp seeds were used as food in China. Cannabis is Cultivated and Left as an Offering In 1500 BCE Scythians started to cultivate cannabis for weaving cloth. "Sacred Grass" Named One of Five Sacred Plants in India Cannabis is called "Sacred Grass" in the Hindu sacred text Arthava-Veda and named one of the five sacred plants of India. Hemp Use Spreads Throughout Europe Marijuana Comes to the New World

Toke of the Town - Study: Marijuana Doesn't Affect Driving Performance It's something most seasoned pot smokers already know, but still it's nice to get more scientific confirmation: Marijuana doesn't make you wreck your car. Subjects show almost identical driving skills just before and just after smoking marijuana, according to a study published in the March issue of the Journal of Psychoactive Drugs. Investigators from Hartford Hospital in Connecticut and the University of Iowa Carver College of Medicine measured the simulated driving performance of 85 people in a double-blind, placebo controlled trial. Volunteers responded to various simulated events associated with auto crash risk, such as avoiding a driver who was entering an intersection illegally, deciding to stop or go through a changing traffic light, responding to the presence of emergency vehicles, avoiding colliding with a dog who entered into traffic, and maintaining safe driving during a secondary (in-the-car) sound distraction. More links from around the web!

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