PLoS Biology : Publishing science, accelerating research A Peer-Reviewed, Open Access Journal Current Issue PLOS Biology is a peer-reviewed, open-access journal featuring research articles of exceptional significance in all areas of biological science, from molecules to ecosystems. The Cell and its Organelles Lists of Nobel Prizes and Laureates The Cell and its Organelles Play the Incredible Megacell Game About the game An ultracentrifuge is used for separating the organelles in the cell according to their size, shape and density. The Nobel Prize The 1974 Nobel Laureates in Physiology or Medicine developed methods that made it possible to see and identify organelles, the specialised compartments inside all our cells.Read More ยป Share this: Share on facebook Share on google_plusone_share Share on twitter More Sharing Services Share on email To cite this pageMLA style: "The Cell and its Organelles". Recommended: The Legacy of Alfred Nobel On 27 November 1895 Alfred Nobel signed his last will in Paris. Play the Blood Typing Game Try to save some patients and learn about human blood types! Unlocking the Secrets of Our Cells Discover the 2012 awarded research on stem cells and cell signalling. Contact E-mail us Press Sitemap A-Z Index Frequently Asked Questions Terms Follow Contact | Press | Sitemap | FAQ | Terms
Scientists observe single gene activity in living cells in detail for first time Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition of Science, Einstein scientists were able to follow, in real time, the process of gene transcription, which occurs when a gene converts its DNA information into molecules of messenger RNA (mRNA) that go on to make the protein coded by the gene. Robert Singer, Ph.D., co-director of the Gruss Lipper Biophotonics Center at Einstein and professor and co-chair of anatomy and structural biology, is senior author of the paper. The study's lead author is Daniel Larson, Ph.D., previously a member of Dr. Using florescent proteins, the researchers were able to follow mRNA activity by inserting DNA sequences into a gene in live yeast cells. This research was funded by the National Institutes of Health and the National Institute of General Medical Sciences.
The PCR Method - a DNA Copying Machine Lists of Nobel Prizes and Laureates The PCR Method - a DNA Copying Machine Play the Eye of the Donkey Game About the game PCR is a method by which a few fragments of DNA can be duplicated into millions in a couple of hours. The Nobel Prize The 1993 Nobel Prize in Chemistry was awarded for the invention of PCR, a method that made it possible to copy a large numbers of DNA fragments in only a few hours. Share this: Share on facebook Share on google_plusone_share Share on twitter More Sharing Services Share on email To cite this pageMLA style: "The PCR Method - a DNA Copying Machine". Recommended: The Legacy of Alfred Nobel On 27 November 1895 Alfred Nobel signed his last will in Paris. Play the Blood Typing Game Try to save some patients and learn about human blood types! Unlocking the Secrets of Our Cells Discover the 2012 awarded research on stem cells and cell signalling. Contact E-mail us Press Sitemap A-Z Index Frequently Asked Questions Terms Follow Contact | Press | Sitemap | FAQ | Terms Follow us:
DAVID: Gene Functional Classification What does this tool do? Quickly translate given gene IDs to corresponding gene names in a batch way Provide links for each genes to DAVID Gene Report for in-depth information Search functionally related genes within user's input gene list or genome Key Concepts of "Search Related Genes" Any given gene is associating with a set of annotation terms. If genes share similar set of those terms (annotation profile), they are most likely involved in similar biological mechanisms. Find Related Genes Tool is very different and complementary to the common gene clustering methods, such as homologous genes based on sequence similarity; protein families based on one common biological activity.
Cell Models For life all cells have basic needs. Cells have diverged in their structure and function to accommodate these survival requirements. Here are some KEY TERMS to help you think, explore and search for similarities and significant differences that have become the characteristics of eukaryote (animal, plant) and prokaryotic (bacteria) cells. Examples might be searching: eukaryote prokaryote reproduction or animal plant cell energy. Reproduction / cell division Energy trapping, storage and consumption Form / shape / structure Cell specialization Compartmentalization of cell functions Communication within and beyond the cell Cell / organism survival How Water Shapes DNA Water molecules surround the genetic material DNA in a very specific way. Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have discovered that, on the one hand, the texture of this hydration shell depends on the water content and, on the other hand, actually influences the structure of the genetic substance itself. These findings are not only important in understanding the biological function of DNA; they could also be used for the construction of new DNA-based materials. The DNA's double helix never occurs in isolation; instead, its entire surface is always covered by water molecules which attach themselves with the help of hydrogen bonds. "We've been able to verify that some of the water is bound stronger whereas other molecules are less so," notes Dr. Analyses of the genetic material were conducted at the HZDR by the doctoral candidate Hassan Khesbak. Oscillations of the water bonds in the hydration shell of the double helix can be excited by infrared light.
All Non-Africans Part Neanderthal, Genetics Confirm If your heritage is non-African, you are part Neanderthal, according to a new study in the July issue of Molecular Biology and Evolution. Discovery News has been reporting on human/Neanderthal interbreeding for some time now, so this latest research confirms earlier findings. Damian Labuda of the University of Montreal's Department of Pediatrics and the CHU Sainte-Justine Research Center conducted the study with his colleagues. "This confirms recent findings suggesting that the two populations interbred," Labuda was quoted as saying in a press release. The ancestors of Neanderthals left Africa about 400,000 to 800,000 years ago. Neanderthals possessed the gene for language and had sophisticated music, art and tool craftsmanship skills, so they must have not been all that unattractive to modern humans at the time. This work goes back to nearly a decade ago, when Labuda and his colleagues identified a piece of DNA, called a haplotype, in the human X chromosome that seemed different.