About This page includes information about the aims and scope of BMC Bioinformatics, editorial policies, open access and article-processing charges, the peer review process and other information. For details of how to prepare and submit a manuscript through the online submission system, please see the instructions for authors. Scope BMC Bioinformatics is an open access, peer-reviewed journal that considers articles on all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology. BMC Bioinformatics is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. BMC series - open, inclusive and trusted. Editorial team Executive Editor Irene Pala Editorial Board Manager Paul Lambert Senior Managing Editor Diana Marshall Open access Indexing services e.g.
www.zo.utexas.edu/faculty/antisense/tree.pdf Brain's Dumped DNA May Lead to Stress, Depression Humans and other mammals react to stressful situations through a series of well-orchestrated evolutionary adaptations. When faced with a predator looking for its next meal, or with worry of losing a job, our bodies release a cascade of stress hormones. Our heart rate spikes, breath quickens, muscles tense up and beads of sweat appear. This so-called “fight-or-flight” response served our ancestors well, but its continual activation in our modern-day lives comes with a cost. Each of our cells contains hundreds of small bean-shaped mitochondria — subcellular structures, or organelles, that provide the energy needed for normal functioning. But our fight-or-flight response places extreme demands on the mitochondria. The genetic cast-offs are not just inert cellular waste. To demonstrate psychological stress can cause mitochondrial DNA to be released by cells, Picard and his team devised a quick stress test. But how was this inflammation triggered by mitochondrial DNA leaking out of cells?
9 Key Components of the Shift to Higher Consciousness This article originally appeared in WakingTimes.com. Facing considerable political, economic, social and ecological crises, the human race is desperate for a transformation and a new direction. Business as usual ensures that we are doomed to run a course of half-conscious self-destruction, as man-made catastrophes multiply and stress mounts in every aspect of life. We must overthrow our ignorance, as it has become a fearful master, goading us into war, pollution, waste and exploitation. The social problems and entrenched patterns at the source of global issues are too vast and complex to be solved at the personal level, yet, paradoxically, the personal transformation of the individual offers a lonesome opportunity to avert the catastrophes we are engineering for ourselves. The shift. Personal evolution is both the great duty and the great joy of all human beings and is a process of divine significance, frequently unfolding in overlapping stages and related developments. 1. 2. 3. 4. 5.
DIY Skylights From Used Water Bottles Replace 50-Watt Bulbs Image via YouTube video An ingenious invention by an engineer in Brazil has made an enormous difference in his town. Simply placing a bottle of water in a hole in the ceiling can light up a room with the same brightness as a 50-watt light bulb! >> WATCH SLIDESHOW: 13 Really Cool Lighting Ideas (Slideshow) I think the part that made it most convincing was the bucket comparison -- when they took the buckets off the bottles to show what a difference they make in lighting the room, my jaw dropped open. While it's obvious that these only work for certain types of structures, and only provide extra light when the sun is out, it shows that you don't have to construct a complex skylight in your roof to get some daylight into your home. And to hear that the bottles are lasting years without needing any maintenance at all is exciting. What a great bottle-reuse-zero-electricity idea! UPDATE: The project is being called Liter of Light.
Panic Attack Symptoms + 10 Unexpected Panic Attack Triggers Have you ever experienced panic attack symptoms? If you have, then you know that the sensations are so intense it feels like you could be having a heart attack or other serious health issue. Panic attacks are characterized by a fear of losing control or surviving a disaster, even though there is no real danger in that moment. There are many possible panic attack triggers, from bacterial infections to low blood sugar levels. If you aren’t familiar with the most common panic attack symptoms and some possible panic attack causes, a panic attack will certainly take you by surprise and feel like a life-threatening occurrence. Deconstructing a Panic Attack + Panic Attack Symptoms A panic attack is an intense and sudden development of fear or anxiety. Panic Attack vs Anxiety Attack: How Are They Different? Ever wonder, “What is an anxiety attack?” Signs of an anxiety attack vs. panic attack are important to differentiate. FatigueHypervigilanceRestlessnessIrritability What is a panic attack? Yes.
The Reptilian Aliens and the Council of the 13 'Royal' Families Excerpts from Blue Blood, True Blood: Conflict & Creation The leader of the Earth's Illuminati is called the "Pindar". ... Excerpts from Blue Blood, True Blood: Conflict & Creation The leader of the Earth's Illuminati is called the "Pindar". The Pindar is a member of one of the 13 ruling Illuminati families, and is always male. The title, Pindar, is an abbreviated term for "Pinnacle of the Draco". Symbolically, this represents the top of power, control, creation, penetration, expansion, invasion, and fear. The holder of this rank reports to the purebred Reptilian leader in the inner Earth. Recently, there are reports that the Marquis de Libeaux is the Pindar, but this is disinformation. He is based in Germany near Frankfurt. Interestingly, there is a winery on the east end of Long Island, not far from Montauk Point, called Pindar Vineyards. This fits nicely into the plan, as this area will be a part of the capital district of the Earth/United Nations in the Empire State! Publicly, Mr.
Interesting High-speed Video Clips 's Stages - Early, Middle, Late Dementia Symptoms Alzheimer’s disease typically progresses slowly in three general stages: early, middle and late (sometimes referred to as mild, moderate and severe in a medical context). Since Alzheimer’s affects people in different ways, each person may experience symptoms — or progress through the stages — differently. Subscribe to our e-newsletter to learn how you can help those affected by Alzheimer's. Overview of disease progression Did you know? People with cognitive changes caused by Mild Cognitive Impairment (MCI) have an increased risk of developing Alzheimer's or another dementia. Learn More The symptoms of Alzheimer's disease worsen over time, although the rate at which the disease progresses varies. The stages below provide an overall idea of how abilities change once symptoms appear and should only be used as a general guide. The stages are separated into three categories: mild Alzheimer's disease, moderate Alzheimer's disease and severe Alzheimer's disease. Early-stage Alzheimer's (mild)
Internet Sacred Text Archive Home A Sense of Scale: Absolute Zero By Glenn Elert Posted 01.08.08 NOVA At roughly minus 460°F, absolute zero is abysmally cold, yet at least we can imagine it. Being only a few hundred degrees below zero, it's in the realm of something we can put our minds around. This is not true of the opposite of absolute zero, the theoretical highest possible temperature. In conventional physics, this is approximately 100 million million million million million degrees. In this interactive, get a taste of temperatures from absolute zero to absolute hot, and see why, for instance, even the core of the sun is relatively "chilly" compared to what many physicists believe the temperature of the universe was an instant after the Big Bang. Launch Interactive Travel from absolute zero to what may be the highest temperature of all. This feature originally appeared on the site for the NOVA program Absolute Zero. Glenn Elert is Research Coordinator and Webmaster for the Physical Science Department of Midwood High School at Brooklyn College. Images
Attention-Deficit/Hyperactivity Disorder: Is it Time to Reappraise the Role of Sugar Consumption? New Obama Advisor John Podesta An Advocate For UFO Disclosure For all of you who hope the U.S. government will lift the veil on its alleged stockpile of evidence that Earth is being visited by extraterrestrials -- take heart. This week, former Clinton chief of staff and UFO advocate John Podesta was named as President Obama's newest advisor. Podesta, 64, has more than once publicly urged the U.S. government to release any UFO files that could help scientists determine "the real nature of this phenomenon." Podesta's stance on UFOs can be seen in the following video clip from the 2009 James Fox film, "I Know What I Saw." Podesta spoke at a 2002 news conference at the National Press Club in Washington, D.C., where he called upon the U.S. government "to declassify [UFO] records that are more than 25 years old." Adding more fuel to the fire, Podesta wrote the foreword to Leslie Kean's 2010 New York Times bestseller, "UFOs: Generals, Pilots, And Government Officials Go On The Record": Drone SecrecyNSA SpyingAfghanistanThe American Political SystemUFOs
Cell Size and Scale Some cells are visible to the unaided eye The smallest objects that the unaided human eye can see are about 0.1 mm long. That means that under the right conditions, you might be able to see an ameoba proteus, a human egg, and a paramecium without using magnification. A magnifying glass can help you to see them more clearly, but they will still look tiny. Smaller cells are easily visible under a light microscope. To see anything smaller than 500 nm, you will need an electron microscope. Adenine The label on the nucleotide is not quite accurate. How can an X chromosome be nearly as big as the head of the sperm cell? No, this isn't a mistake. The X chromosome is shown here in a condensed state, as it would appear in a cell that's going through mitosis. A chromosome is made up of genetic material (one long piece of DNA) wrapped around structural support proteins (histones). Carbon The size of the carbon atom is based on its van der Waals radius.