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Benzodiazepine

Benzodiazepine
A benzodiazepine /ˌbɛnzɵdaɪˈæzɨpiːn/ (sometimes colloquially "benzo"; often abbreviated "BZD") is a psychoactive drug whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which has also marketed the benzodiazepine diazepam (Valium) since 1963.[1] In general, benzodiazepines are safe and effective in the short term, although cognitive impairments and paradoxical effects such as aggression or behavioral disinhibition occasionally occur. A minority react reverse and contrary to what would normally be expected. There is controversy concerning the safety of benzodiazepines in pregnancy. Medical uses[edit] Panic disorder[edit] Benzodiazepines are usually administered orally; however, very occasionally lorazepam or diazepam may be given intravenously for the treatment of panic attacks.[17] Insomnia[edit]

Oseltamivir Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B (flu).[3] Many medical organizations recommend it in people who have complications or are at high risk of complications within 48 hours of first symptoms of infection.[4] They recommend it to prevent infection in those at high risk, but not the general population.[4] The Centers for Disease Control and Prevention (CDC) recommends that clinicians use their discretion to treat those at lower risk who present within 48 hours of first symptoms of infection.[4][5][6] It is taken by mouth, either as a pill or liquid.[3] Medical use[edit] High-risk people[edit] A 2014 review in the New England Journal of Medicine had recommended that all people admitted to intensive care units during influenza outbreaks with a diagnosis of community-acquired pneumonia receive oseltamivir until the absence of influenza infection is established by PCR testing.[29] Prevention[edit]

Conjugated estrogens Medical uses[edit] CEEs are a form of hormone therapy used in women.[17] It is used most commonly in postmenopausal women who have had a hysterectomy to treat hot flashes, and burning, itching, and dryness of the vagina and surrounding areas.[18] It must be used in combination with a progestogen in women who have not had a hysterectomy.[1] For women already taking the medication, it can be used to treat osteoporosis, although it is not recommended solely for this use.[19] Some lesser known uses are as a means of high-dose estrogen therapy in the treatment of breast cancer in both women and men and in the treatment of prostate cancer in men.[20][21] It has been used at a dosage of 2.5 mg three times per day (7.5 mg/day total) for prostate cancer.[22][23] Available forms[edit] Contraindications[edit] Contraindications of CEEs include breast cancer and a history of venous thromboembolism, among others.[citation needed] Side effects[edit] Overdose[edit] Interactions[edit] Pharmacology[edit]

How Long Are Antibiotics Good For Past the Expiration Date? << Go back to blog Let’s face it, prescriptions can be expensive. That’s why it’s understandable why anyone would be reluctant to toss medications if they’re past the expiration date. So, the question is: how long are antibiotics good for? And can you take expired antibiotics? Keep reading to find out. What Does the Expiration Date Represent? Like food and beverage products, prescription and over-the-counter (OTC) drugs have expiration dates. How Long Are Antibiotics Good For Once Expired? According to the FDA, in order to stay prepared for public health emergencies, governments and even some private sector partners may stockpile medical countermeasures (MCMs). Another study by Cantrell and colleagues tested the effectiveness of eight medications. Can You Take Expired Antibiotics? Research does support that prescription and OTC drugs can still retain their potency well beyond the expiration date. Final Word So, how long are antibiotics good for past the expiration date?

8 Strategies for Swallowing Pills We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process. Lots of people have difficulty swallowing pills. Dry mouth, difficulty swallowing (dysphagia), and fear of choking can all make the act of taking your prescribed medication feel next to impossible. And for young children who’ve never swallowed pills before, the very idea of gulping down a tablet without chewing can be a hard concept to understand, let alone accomplish. If you’re one of the many people who have difficulty swallowing pills, read on. Plus, we’ll provide eight new pill-swallowing strategies that may make it easier for you and your child. Swallowing isn’t as simple as it looks. Most of the time when you swallow, you don’t have to think about the reflexes at work. The globus sensation When you feel stress or anxiety, you may experience something called “globus sensation.” Alternative strategies Practice with sprinkles Helpful products 1.

Pill Swallowing by Adults With Dysphagia | Otolaryngology | JAMA Otolaryngology–Head & Neck Surgery Objective To evaluate differences in swallowing physiology and safety in patients with dysphagia between conventional tablets and a new method of tablet transportation, orally disintegrating technology (ODT) (RapiTab; Schwarz Pharma Inc, Milwaukee, Wis). Design The study observed a single group, crossover design. Setting Outpatient clinic within an academic teaching hospital. Participants A total of 36 adult dysphagic patients referred to the clinic. Interventions All subjects underwent simultaneous nasopharyngeal endoscopic evaluation, surface electromyographic (sEMG) measurement, and respiratory monitoring during swallowing. Results Significant differences included greater sEMG amplitude and longer apneic duration when swallowing a conventional tablet compared with the ODT (P<.001). Conclusions Patients with dysphagia frequently complain of trouble swallowing medication. The study followed a randomized, single-group, crossover design. Patient preference rating Financial Disclosure: None.

Walmart, CVS face trial for putting sham homeopathic products next to real meds Pharmacy giants CVS and Walmart will have to face trials over claims that placing ineffective homeopathic products alongside legitimate over-the-counter medicines on store shelves deceives consumers into thinking that the pseudoscientific products are akin to evidence-based, Food and Drug Administration-approved drugs. The claims come from the nonprofit organization Center for Inquiry (CFI), which filed nearly identical lawsuits against CVS and Walmart in 2018 and 2019, respectively, to try to boot homeopathic products from pharmacy aisles for good. CFI claimed that deceptive placement of the water-based products violated the District of Columbia Consumer Protection Procedures Act (CPPA). Two lower courts initially dismissed the lawsuits. But, in a unanimous ruling last week, a panel of three judges for the District of Columbia's highest court overturned the dismissals in a consolidated appeal, allowing the trials to move forward. At best, homeopathic products are watery placebos.

FDA confirms toxicity of homeopathic baby products; Maker refuses to recall [Updated] After investigating reports that more than 400 babies were sickened and 10 died in connection with homeopathic teething products, the Food and Drug Administration confirmed Friday that it had indeed found elevated levels of the toxic substance, belladonna, in the products. Belladonna, also known as deadly nightshade, was the prime suspect of the investigation from the beginning, which Ars reported about last fall. Nevertheless, the products’ maker, Hyland’s, would not agree to recall the products when it was notified of the FDA’s conclusion, the agency reported. In a response to Ars, Hyland's has acknowledged that there are some inconsistencies in the amount of belladonna in its products, but the company said that it has not seen any evidence from the FDA indicating that the elevated levels were toxic or excessive. “The current data [seen by the company] indicate that the measured samples all fall well within an accepted margin of safety,” Hyland’s spokesperson, Mary Borneman, told Ars.

Why I’m Fighting the Deadly Alberta Drug Model Addiction treatment is not a neutral field of medicine. It’s highly politicized, with conservatives tending to ignore systemic problems, blame users and focus on treatment and abstinence, and liberals tending to accept people the way they are and focus on measures to keep them alive. Both sides can argue problems with the other’s positions. I have known people who died after being coerced into treatment — and one person whose family was gaslit by the facility they attended immediately following their death. I am not an addiction expert. There are many frequent examples of pseudoscience. Studies the government has relied on show survivor bias, showcasing only people who survive treatment while looking past the many thousands of participants who die. And they relentlessly ignore the positive results of evidence-based practices like supervised consumption sites and prescribed regulated drugs. Why protest the Alberta Recovery Conference?

Dimenhydrinate Anti-emetic and antihistamine medication Dimenhydrinate, sold under the brand name Dramamine, among others, is an over-the-counter medication used to treat motion sickness and nausea. Dimenhydrinate is a theoclate salt composed of diphenhydramine (an ethanolamine derivative) and 8-chlorotheophylline (a chlorinated theophylline derivative) in a 1:1 ratio.[2] Dimenhydrinate was introduced to the market by G.D. Medical uses[edit] Dimenhydrinate is an over-the-counter (OTC) antihistamine indicated for the prevention and relief of nausea and vomiting from a number of causes, including motion-sickness and post-operative nausea.[2] Side effects[edit] Common side effects may include:[5] DrowsinessDry mouth, nose, or throatConstipationBlurred visionFeeling restless or excited (especially in children) Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk of cognitive decline and dementia in older people.[6][7]

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