PLoS Biology : Publishing science, accelerating research

Public Library of Science: Open Access The Case for Open Access Open Access (OA) stands for unrestricted access and unrestricted reuse. Here’s why that matters. Most publishers own the rights to the articles in their journals. Anyone who wants to read the articles must pay to access them. Anyone who wants to use the articles in any way must obtain permission from the publisher and is often required to pay an additional fee.

Scientists observe single gene activity in living cells in detail for first time Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition of Science, Einstein scientists were able to follow, in real time, the process of gene transcription, which occurs when a gene converts its DNA information into molecules of messenger RNA (mRNA) that go on to make the protein coded by the gene. Robert Singer, Ph.D., co-director of the Gruss Lipper Biophotonics Center at Einstein and professor and co-chair of anatomy and structural biology, is senior author of the paper. The study's lead author is Daniel Larson, Ph.D., previously a member of Dr.

Accelerating Future There isn’t enough in the world. Not enough wealth to go around, not enough space in cities, not enough medicine, not enough intelligence or wisdom. Not enough genuine fun or excitement. DAVID: Gene Functional Classification What does this tool do? Quickly translate given gene IDs to corresponding gene names in a batch way Provide links for each genes to DAVID Gene Report for in-depth information Search functionally related genes within user's input gene list or genome Key Concepts of "Search Related Genes" Any given gene is associating with a set of annotation terms. If genes share similar set of those terms (annotation profile), they are most likely involved in similar biological mechanisms.

How Water Shapes DNA Water molecules surround the genetic material DNA in a very specific way. Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) have discovered that, on the one hand, the texture of this hydration shell depends on the water content and, on the other hand, actually influences the structure of the genetic substance itself. These findings are not only important in understanding the biological function of DNA; they could also be used for the construction of new DNA-based materials. The DNA's double helix never occurs in isolation; instead, its entire surface is always covered by water molecules which attach themselves with the help of hydrogen bonds.

Science and technology research news « Prev | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Next » Detecting corrosion and fatigue during service A new project, CORFAT (Cost effective corrosion and fatigue monitoring for transport products SCP7-GA-2008-218637), looks to develop new monitoring technology based on acoustic emission testing (AT) combined with follow-up NDT (non-destructive testing) to detect defects such as corrosion or cracks in the structure of surface transport products (ships, railway tank cars, road tankers). All Non-Africans Part Neanderthal, Genetics Confirm If your heritage is non-African, you are part Neanderthal, according to a new study in the July issue of Molecular Biology and Evolution. Discovery News has been reporting on human/Neanderthal interbreeding for some time now, so this latest research confirms earlier findings. Damian Labuda of the University of Montreal's Department of Pediatrics and the CHU Sainte-Justine Research Center conducted the study with his colleagues.

44 tips cards for photographers to cut out and keep or browse on your phone! Digital Camera magazine has been putting pop-out tips cards on its covers for dozens of issues (find out how to subscribe below), so we thought why not put our favorites online? We've picked out a selection of cards to keep you busy during the coronavirus crisis, and they include camera theory, tips for portraits and people shots, ideas for things to photograph in the garden and little projects you can tackle at home. They've been sized specially for easy on-screen viewing, and not just on a desktop computer but on the smaller screen of a tablet or a smartphone. And if you can't easily read the text on your phone, just turn it sideways. For those who prefer paper to pixels, see our diagram below.

Methods and protocols in molecular biology - GFP Applications Page designed by Wallace Marshall, Yale University. {*style:<b>Added: 28-Nov-1999 Hits: 982 Rating: 7.33 Votes: 3 [ Rate It ] </b>*} - Contains many molecular biology protocols as well as some Drosophila protocols. Protocols are downloadable Word files. {*style:<b>Added: 26-Sep-2003 Hits: 447 Rating: 10 Votes: 1

New Self-Cloning Lizard Found in Vietnam Restaurant {*style:<b>You could call it the surprise du jour: A popular food on Vietnamese menus has turned out to be a lizard previously unknown to science, scientists say. </b>*} What's more, the newfound is no run-of-the-mill reptile —the all-female species reproduces via cloning, without the need for male lizards. Single-gender lizards aren't that much of an oddity: About one percent of lizards can reproduce by parthenogenesis, meaning the females spontaneously ovulate and clone themselves to produce offspring with the same genetic blueprint.

PCR Virtual Lab Primers are short pieces of DNA that are made in a laboratory. Since they're custom built, primers can have any sequence of nucleotides you'd like. In a PCR experiment, two primers are designed to match to the segment of DNA you want to copy. Through complementary base pairing, one primer attaches to the top strand at one end of your segment of interest, and the other primer attaches to the bottom strand at the other end. In most cases, 2 primers that are 20 or so nucleotides long will target just one place in the entire genome. Primers are also necessary because DNA polymerase can't attach at just any old place and start copying away.

The Biology Project: Cell Biology en español Cell Membranes Learn that membranes are fluid, with components that move, change, and perform vital physiological roles as they allow cells to communicate with each other and their environment. Cell Signaling Learn that living organisms constantly receive and interpret signals from their environment. Cells of multi-cellular organisms also receive signals from other cells, including signals for cell division and differentiation. Studying Cells Introduce yourself to the cell as the fundamental unit of life and the scientific method. The Cell Cycle & Mitosis Understand the events that occur in the cell cycle and the process of mitosis that divides the duplicated genetic material creating two identical daughter cells.

FISH pour le diagnostic préimplantatoire génétique This article describes the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to pre-implantation genetic diagnosis (PGD) in a clinical setting. Date Published: 2/23/2011, Issue 48; doi: 10.3791/2570 Keywords: Medicine, Issue 48, Fluorescence in situ hybridization, Pre-implantation genetic diagnosis, PGD, Sex determination, Translocations, Chromosome aneuploidy Scriven, P.