Memory implantation is now officially real The movie Inception is getting closer to reality. By planting false memories into the minds of mice, neuroscientists at MIT have created the first artificially implanted memories. And they've brought us closer to understanding the fallibility of human recollection. When we experience something, say a trip to the park, a memory of the event is stored in a constellation of interconnected neurons in our brains called an "engram," or memory trace. In the 1940s, Canadian neurosurgeon Wilder Penfield delivered electrical shocks to the temporal lobes of patients about to undergo brain surgery, and his subjects reported the sudden recollection of specific memories. How To Implant a Memory In a study published in the latest issue of Science, a team of researchers led by MIT neuroscientist and Nobel Laureate Susumu Tonegawa demonstrates its ability to isolate and activate engrams in a mouse's memory-rich hippocampus. Here's the brilliant bit. Next comes the memory implantation.
3D Printed Body Parts Go Mainstream 3D printing technology has been around for two decades, but the price has come down in recent years and more people have been able to make use of it. Consequently, we've started to be able to really tap into its vast potential. 3D printed products are being spewed out left, right and center; from the building blocks of houses to replica shark skin. It almost seems as though the capabilities are endless, and the technology is not anticipated to slow down any time soon. One really exciting application of 3D printing is the generation of body parts. The level of detail that this technology can produce often supersedes that of traditional methods, offering patients a superior fit or design, and they can often be produced at an impressively low cost. Researchers have turned to 3D printing to produce a wide variety of body parts. Image credit: Washington University in St Louis. Image credit: Not Impossible/ Project Daniel. Image credit: UMC Utrecht.
Michael Anissimov: Transhumanism Has Already Won I just spent 10 minutes reading this excellent article on Michael Anissimov’s Accelerating Future blog and had to re-post it in full — it is that good! Enjoy: Transhumanism Has Already Won by Michael Anissimov It’s 2010, and transhumanism has already won. At their base, the world’s major two largest religions — Christianity and Islam — are transhumanistic. Humanity, as it stands today, is a seed, a bridge. The mainstream has embraced transhumanism. Everything is Not Alright I am tremendously sympathetic to transhumanism’s critics and detractors, more so than most transhumanists I have met. People are basically nice when they’re well-fed, and damn evil when they’re hungry. Even technologies readily available today, but rarely used — such as the direct electrical stimulation of the pain and pleasure centers of the human brain — could become fearsome new plagues on humanity if in the hands of the wrong political or religious fanatics. They Like Us? Good and evil are ideas.
Exploiting Bacteria to Produce "Living Materials" A group of researchers at the Massachusetts Institute of Technology have unveiled a system whereby bacterial cells are engineered in such a way that they incorporate specific non-living materials into their biofilms, creating a "living material". Biofilms are generated when bacteria cluster together and stick onto a surface. Often the bacteria will secrete substances that assist in this adherence, such as proteins and carbohydrate polymers (called polysaccharides) which form a slime. Researchers have generated a system whereby they can exploit these biofilm producers by cajoling the bacteria into incorporating non-living materials into their biofilms, such as gold nanoparticles. In a paper published in Nature, researchers led by Timothy Lu selected the common bacterial species E. coli on the basis that it produces biofilms that contain "curli fibers", which are chains composed of a curlin subunit called CsgA. But that's not all they did.
Spray-On Nanofibres Bind Surgical Wounds Polymer nanofibres can be sprayed onto surgical incisions, sealing them to prevent infection. The process may be used in addition to sutures, but may also remove the need for them in some cases. The potential of mats of polymer nanofibers has been recognized for some time. They can seal up wounds, biodegrade so they don't need to be removed, and be impregnated with slow release drugs. Nanofiber mats also have potential as scaffolds on which to grow tissue from stem cells. Mats can be made through electrospinning where fine fibers are drawn from a liquid with an electric field, but the University of Maryland's Professor Peter Kofinas notes this “requires specialized equipment, high voltages and electrically conductive targets”. To idea itself is not new. Macro Letters reports the mats capacity to seal not only cuts to the skin, but also the lungs, intestines and livers of pigs. A technique using a related concept, aerosol delivery of skin cells to burn victims, is under clinical trial.
Transhumanism For the United Nations, relevance may be almost as perilous as irrelevance. In the span of a year, the Bush administration went from taunting the world body to begging for its help. A beefed-up U.N. team will soon arrive in Baghdad to advise the Iraqi government on reconstruction, social services, and human rights and directly assist with elections. At the same time, U.N. peacekeeping missions are sprouting or expanding in Burundi, Democratic Republic of the Congo, Haiti, and Ivory Coast. Indeed, by the end of 2004, more blue helmets will likely be in action than at any time in history. Although some U.N. backers revel in the growing global reliance on the world body, now is no time to get smug. The idea that the United Nations can stumble along in its atrophied condition has powerful appeal in capitals around the world -- and even in some offices at U.N. headquarters. Regrettably, most of those who could change the organization have an interest in resisting reform. Much U.N.
Magnet Assisted Transfection - Cells Transfection - LIFE SCIENCE | Order To perform transfection with Magnetofection technology, you only need to buy the magnetic plate once and the reagents (magnetic particle formulations) appropriate to your needs. There is no further equipment required, so Magnetofection is an economical solution, especially for hard-to-transfect cells. MagnetofectionTM is a novel, simple and highly efficient method to transfect cells In Vitro. Two Basic types of ready-to-use Magnetofection™ reagents: PolyMAG is a universally applicable magnetic particle preparation for high efficiency nucleic acid delivery. CombiMAG is a magnetic particle preparation designed to be combined with any commercially available transfection reagent such as polycations and lipids and can be associated with plasmid DNA, antisense oligonucleotides, siRNAs or viruses. To perform transfection with Magnetofection technology, you only need to buy the magnetic plate once and the reagents (magnetic particle formulations) appropriate to your needs.
Bionic Pancreas Promises Big Boost in Health, Quality of Life for Type 1 Diabetics Diabetes, despite affecting nearly 350 million people worldwide, is not really a controlled illness. Those who have the type 1 form of the illness, in which the pancreas fails to produce the insulin that processes glucose in the bloodstream, often face serious eye, kidney and cardiovascular problems. Perhaps the worst outcome is one rarely mentioned in public discourse about the disease: the possibility of dying in the middle of the night due to a miscalculated dose of insulin that can’t be caught when the patient is asleep. The thing is, it’s not easy to dose insulin. When the American Diabetes Association assures patients on its website that, “With the help of insulin therapy and other treatments, even young children can learn to manage their condition and live long, healthy lives,” the claim is more optimistic than realistic. For the study, 20 adults wore the device for five days as they went about their daily lives in the company of a study nurse. Photos: Boston University, DiaTribe