Genetic Disorders Genetics Course|Biology Course Summary This course is based on 7.03 Genetics, Fall 2004 made available by Massachusetts Institute of Technology: MIT OpenCourseWare under the Creative Commons BY-NC-SA license. This course discusses the principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. The topics include: structure and function of genes, chromosomes and genomes, biological variation resulting from recombination, mutation, and selection, population genetics, use of genetic methods to analyze protein function, gene regulation and inherited disease. Reading Material 1. Course Material Not available. Other Resources 1. Software The PCR Method - a DNA Copying Machine Lists of Nobel Prizes and Laureates The PCR Method - a DNA Copying Machine Play the Eye of the Donkey Game About the game PCR is a method by which a few fragments of DNA can be duplicated into millions in a couple of hours. The Nobel Prize The 1993 Nobel Prize in Chemistry was awarded for the invention of PCR, a method that made it possible to copy a large numbers of DNA fragments in only a few hours. Share this: Share on facebook Share on google_plusone_share Share on twitter More Sharing Services Share on email To cite this pageMLA style: "The PCR Method - a DNA Copying Machine". Recommended: The Legacy of Alfred Nobel On 27 November 1895 Alfred Nobel signed his last will in Paris. Play the Blood Typing Game Try to save some patients and learn about human blood types! Unlocking the Secrets of Our Cells Discover the 2012 awarded research on stem cells and cell signalling. Contact E-mail us Press Sitemap A-Z Index Frequently Asked Questions Terms Follow Contact | Press | Sitemap | FAQ | Terms Follow us:
3D Animation Library Animations can be viewed within your web browser or downloaded for play from your computer. In some genes the protein-coding sections of the DNA ("exons") are interrupted by non-coding regions ("introns"). RNA splicing removes the introns from pre mRNA to produce the final set of instructions for the protein. Transcript: As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. This editing process is called splicing, which involves removing the introns, leaving only the yellow, protein-coding regions, called exons. RNA splicing begins with assembly of helper proteins at the intron/exon borders. This process is repeated for every intron in the RNA.
Mendelian Genetics An important question to answer in any genetic experiment is how can we decide if our data fits any of the Mendelian ratios we have discussed. A statistical test that can test out ratios is the Chi-Square or Goodness of Fit test. Chi-Square Formula Degrees of freedom (df) = n-1 where n is the number of classes Let's test the following data to determine if it fits a 9:3:3:1 ratio. Number of classes (n) = 4 df = n-1 + 4-1 = 3 Chi-square value = 0.47 Enter the Chi-Square table at df = 3 and we see the probability of our chi-square value is greater than 0.90. A Chi-Square Table Copyright © 2000.
STAR: Biochem - Home StarBiochem is a 3-D protein viewer that allows students to learn key concepts about the biology of proteins in an interactive manner. Unlike traditional 3-D protein viewers which may require installation and significant technical expertise, StarBiochem is an intuitive 3-D protein viewer designed with students in mind. StarBiochem’s user interface was designed to visually represent protein structural information based on the four different levels of protein structure, which mirrors how students get introduced to this topic in class and in textbooks. Using StarBiochem StarBiochem is accessible via the web. Exercises Sample exercises for StarBiochem, covering a range of concepts and difficulty, can be found in Sample Exercise. StarBiochem in Action Image of StarBiochem (Version 2.3) rendering 1A3N (Deoxy Human Hemoglobin)
Virtual Labs BioInteractive’s virtual labs have won several awards, including top honors in the Pirelli INTERNETional Award competition, which recognizes the best multimedia products designed to use the Internet to educate about science and technology. Designed in close consultation with educators and scientists, these virtual labs are fully interactive biomedical laboratory simulations and provide students with skills and techniques used in scientific research. BioInteractive’s series of virtual labs allows students to examine heart patients, analyze DNA sequences, probe the nervous system of a leech, use human antibodies to diagnose disease, and measure physical traits of stickleback fish and anole lizards to examine key concepts in evolution. Each lab provides an interactive environment in which students perform experiments and collect their data, and answer questions to assess their understanding. The labs can be accessed by clicking the icons on the right-hand side of the page.
STAR: Genetics - Home StarGenetics is a Mendelian genetics cross simulator developed at MIT by biology faculty, researched-trained scientists and technologists at MIT's OEIT. StarGenetics allows students to simulate mating experiments between organisms that are genetically different across a range of traits to analyze the nature of the traits in question. Its goal is to teach students about genetic experimental design and genetic concepts. For more information on StarGenetics click here. Using StarGenetics StarGenetics is freely accessible via the web. Overview StarGenetics can be used to teach simple genetics concepts that are appropriate for high school biology students as well as complex genetics concepts that are appropriate for advanced biology undergraduate students.In addition,StarGenetics allows for instructors to customize the exercises presented to the student. Cow Fish Fly Peas Smiley Face Yeast