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Neuron

Neuron
All neurons are electrically excitable, maintaining voltage gradients across their membranes by means of metabolically driven ion pumps, which combine with ion channels embedded in the membrane to generate intracellular-versus-extracellular concentration differences of ions such as sodium, potassium, chloride, and calcium. Changes in the cross-membrane voltage can alter the function of voltage-dependent ion channels. If the voltage changes by a large enough amount, an all-or-none electrochemical pulse called an action potential is generated, which travels rapidly along the cell's axon, and activates synaptic connections with other cells when it arrives. Neurons do not undergo cell division. In most cases, neurons are generated by special types of stem cells. A type of glial cell, called astrocytes (named for being somewhat star-shaped), have also been observed to turn into neurons by virtue of the stem cell characteristic pluripotency. Overview[edit] Anatomy and histology[edit] Related:  Neuroscience

Brain Atlas - Introduction The central nervous system (CNS) consists of the brain and the spinal cord, immersed in the cerebrospinal fluid (CSF). Weighing about 3 pounds (1.4 kilograms), the brain consists of three main structures: the cerebrum, the cerebellum and the brainstem. Cerebrum - divided into two hemispheres (left and right), each consists of four lobes (frontal, parietal, occipital and temporal). – closely packed neuron cell bodies form the grey matter of the brain. Cerebellum – responsible for psychomotor function, the cerebellum co-ordinates sensory input from the inner ear and the muscles to provide accurate control of position and movement. Brainstem – found at the base of the brain, it forms the link between the cerebral cortex, white matter and the spinal cord. Other important areas in the brain include the basal ganglia, thalamus, hypothalamus, ventricles, limbic system, and the reticular activating system. Basal Ganglia Thalamus and Hypothalamus Ventricles Limbic System Reticular Activating System Glia

Brain This article compares the properties of brains across the entire range of animal species, with the greatest attention to vertebrates. It deals with the human brain insofar as it shares the properties of other brains. The ways in which the human brain differs from other brains are covered in the human brain article. Several topics that might be covered here are instead covered there because much more can be said about them in a human context. The most important is brain disease and the effects of brain damage, covered in the human brain article because the most common diseases of the human brain either do not show up in other species, or else manifest themselves in different ways. Anatomy[edit] Cross section of the olfactory bulb of a rat, stained in two different ways at the same time: one stain shows neuron cell bodies, the other shows receptors for the neurotransmitterGABA. Cellular structure[edit] Neurons generate electrical signals that travel along their axons. Evolution[edit]

UCSB scientists discover how the brain encodes memories at a cellular level (Santa Barbara, Calif.) –– Scientists at UC Santa Barbara have made a major discovery in how the brain encodes memories. The finding, published in the December 24 issue of the journal Neuron, could eventually lead to the development of new drugs to aid memory. The team of scientists is the first to uncover a central process in encoding memories that occurs at the level of the synapse, where neurons connect with each other. "When we learn new things, when we store memories, there are a number of things that have to happen," said senior author Kenneth S. "One of the most important processes is that the synapses –– which cement those memories into place –– have to be strengthened," said Kosik. This is a neuron. (Photo Credit: Sourav Banerjee) Part of strengthening a synapse involves making new proteins. The production of new proteins can only occur when the RNA that will make the required proteins is turned on. When the signal comes in, the wrapping protein degrades or gets fragmented.

Cell biology Understanding cells in terms of their molecular components. Knowing the components of cells and how cells work is fundamental to all biological sciences. Appreciating the similarities and differences between cell types is particularly important to the fields of cell and molecular biology as well as to biomedical fields such as cancer research and developmental biology. These fundamental similarities and differences provide a unifying theme, sometimes allowing the principles learned from studying one cell type to be extrapolated and generalized to other cell types. Therefore, research in cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and developmental biology. Processes[edit] Movement of proteins[edit] Endothelial cells under the microscope. Each type of protein is usually sent to a particular part of the cell. Other cellular processes[edit] Internal cellular structures[edit] Techniques used to study cells[edit] Notable cell biologists[edit]

The Learning Brain Gets Bigger--Then Smaller With age and enough experience, we all become connoisseurs of a sort. After years of hearing a favorite song, you might notice a subtle effect that’s lost on greener ears. Perhaps you’re a keen judge of character after a long stint working in sales. Or maybe you’re one of the supremely practiced few who tastes his money’s worth in a wine. Whatever your hard-learned skill is, your ability to hear, see, feel, or taste with more nuance than a less practiced friend is written in your brain. One classical line of work has tackled these questions by mapping out changes in brain organization following intense and prolonged sensory experience. But don’t adopt that slogan quite yet. If you were to look at the side of someone’s brain, focusing on the thin sliver of auditory cortex, it would seem fairly uniform, with only a few blood vessels to provide some bearing. And yet, some aspects of this theory invited skepticism. So what does change? Still, there’s a big question lurking here.

Anatomy Anatomy is the branch of biology concerned with the study of the structure of animals and their parts; it is also referred to as zootomy to separate it from human anatomy. In some of its facets, anatomy is related to embryology and comparative anatomy, which itself is closely related to evolutionary biology and phylogeny.[1] Human anatomy is one of the basic essential sciences of medicine. Definition[edit] Human compared to elephant frame Anatomical chart by Vesalius, Epitome, 1543 The discipline of anatomy can be subdivided into a number of branches including gross or macroscopic anatomy and microscopic anatomy.[4] Gross anatomy is the study of structures large enough to be seen with the naked eye, and also includes superficial anatomy or surface anatomy, the study by sight of the external body features. The term "anatomy" is commonly taken to refer to human anatomy. Animal tissues[edit] A diagram of an animal cell Unlike plant cells, animal cells have neither a cell wall nor chloroplasts.

Meditation found to increase brain size Kris Snibbe/Harvard News Office Sara Lazar (center) talks to research assistant Michael Treadway and technologist Shruthi Chakrapami about the results of experiments showing that meditation can increase brain size. People who meditate grow bigger brains than those who don’t. Researchers at Harvard, Yale, and the Massachusetts Institute of Technology have found the first evidence that meditation can alter the physical structure of our brains. Brain scans they conducted reveal that experienced meditators boasted increased thickness in parts of the brain that deal with attention and processing sensory input. In one area of gray matter, the thickening turns out to be more pronounced in older than in younger people. “Our data suggest that meditation practice can promote cortical plasticity in adults in areas important for cognitive and emotional processing and well-being,” says Sara Lazar, leader of the study and a psychologist at Harvard Medical School. Controlling random thoughts

Neuroscience Neuroscience is the scientific study of the nervous system.[1] Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics, medicine and allied disciplines, philosophy, physics, and psychology. It also exerts influence on other fields, such as neuroeducation[2] and neurolaw. The term neurobiology is usually used interchangeably with the term neuroscience, although the former refers specifically to the biology of the nervous system, whereas the latter refers to the entire science of the nervous system. Because of the increasing number of scientists who study the nervous system, several prominent neuroscience organizations have been formed to provide a forum to all neuroscientists and educators. History[edit] The study of the nervous system dates back to ancient Egypt. Modern neuroscience[edit] Human nervous system

Imagining the Future Invokes Your Memory I REMEMBER my retirement like it was yesterday. As I recall, I am still working, though not as hard as I did when I was younger. My wife and I still live in the city, where we bicycle a fair amount and stay fit. We have a favorite coffee shop where we read the morning papers and say hello to the other regulars. In reality, I’m not even close to retirement. A new study from the January issue of Psychological Science may explain why we are all so optimistic about what’s to come. Cognitive scientists are very interested in people’s “remembered futures.” Still, very little was known until recently about how these simulations work. These are very difficult questions to study in a laboratory—or at least they were until now. Recalling Tomorrow Szpunar and his colleagues began by collecting a lot of biographical detail from volunteers’ actual memories.

The Brain May Disassemble Itself in Sleep Compared with the hustle and bustle of waking life, sleep looks dull and unworkmanlike. Except for in its dreams, a sleeping brain doesn’t misbehave or find a job. It also doesn’t love, scheme, aspire or really do much we would be proud to take credit for. In a provocative new theory about the purpose of sleep, neuroscientist Giulio Tononi of the University of Wisconsin–Madison has proposed that slumber, to cement what we have learned, must also spur the brain’s undoing. Select an option below: Customer Sign In *You must have purchased this issue or have a qualifying subscription to access this content

Is the Purpose of Sleep to Let Our Brains “Defragment,” Like a Hard Drive? | The Crux Neuroskeptic is a neuroscientist who takes a skeptical look at his own field and beyond at the Neuroskeptic blog. Why do we sleep? We spend a third of our lives doing so, and all known animals with a nervous system either sleep, or show some kind of related behaviour. But scientists still don’t know what the point of it is. There are plenty of theories. Some researchers argue that sleep has no specific function, but rather serves as evolution’s way of keeping us inactive, to save energy and keep us safely tucked away at those times of day when there’s not much point being awake. But others argue that sleep has a restorative function—something about animal biology means that we need sleep to survive. Waking up after a good night’s sleep, you feel restored, and many studies have shown the benefits of sleep for learning, memory, and cognition. This illustration, taken from their paper, shows the basic idea: While we’re awake, your brain is forming memories. So what’s the evidence?

Making Sense of the World, Several Senses at a Time Our five senses–sight, hearing, touch, taste and smell–seem to operate independently, as five distinct modes of perceiving the world. In reality, however, they collaborate closely to enable the mind to better understand its surroundings. We can become aware of this collaboration under special circumstances. In some cases, a sense may covertly influence the one we think is dominant. When visual information clashes with that from sound, sensory crosstalk can cause what we see to alter what we hear. Our senses must also regularly meet and greet in the brain to provide accurate impressions of the world. Seeing What You Hear We can usually differentiate the sights we see and the sounds we hear. Beep Baseball Blind baseball seems almost an oxymoron. Calling What You See Bats and whales, among other animals, emit sounds into their surroundings—not to communicate with other bats and whales—but to “see” what is around them. Do You Have Synesthesia?

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