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Academic Video Search Robert H. Goddard was born in Worcester, Massachusetts to Nahum Danford Goddard, a businessman, and Fannie Hoyt Goddard. Early in life, young Robert suffered from pulmonary tuberculosis which kept him out of school for long periods of time. However, he kept up with his studies and was an avid readers. It was after reading H.G. After graduating from school, Robert Goddard applied and was accepted at Worcester Polytechnic Institute. Unfortunately, in early 1913, Goddard became seriously ill with tuberculosis, and had to leave his position at Princeton. Goddard's thoughts on space flight started to emerge in 1915, when he theorized that a rocket would work in a vacuum, and didn't need to push against air in order to fly. Goddard turned his attention to the components of his rockets. Powder rockets were still problematic. Indeed, the flight of Goddard’s rocket on March 16, 1926, at Auburn, Mass., was as significant to history as that of the Wright brothers at Kitty Hawk.

The role of the microbiome in cancer development and therapy Abstract Answer questions and earn CME/CNE The human body harbors enormous numbers of microbiota that influence cancer susceptibility, in part through their prodigious metabolic capacity and their profound influence on immune cell function. Microbial pathogens drive tumorigenesis in 15% to 20% of cancer cases. Even larger numbers of malignancies are associated with an altered composition of commensal microbiota (dysbiosis) based on microbiome studies using metagenomic sequencing. Practical Implications for Continuing Education Maintenance of microbial diversity is critical for human health. Introduction The microbiota that inhabit our gastrointestinal (GI) tract and other anatomic sites can be considered environmental factors to which we are continuously exposed at high doses throughout life. The Human Microbiome Changes in lifestyles and societal norms influence the microbiome at each stage of life. Microbial Pathogens Drive Certain Cancers Immune System and Inflammation DNA Damage

Exercise for people with cancer: a clinical practice guideline | Segal | Current Oncology R. Segal, MD*, C. Zwaal, MSc†, E. Early detection and screening programs and improved medical treatments for certain types of cancer have translated into, or resulted in, more people having a better chance of being cured of their disease or living longer with it. Cancer rehabilitation forms part of the cancer journey. Exercise as a prescription is becoming more of a movement throughout the medical field as observed through Exercise Is Medicine Canada ( There are different types of exercise and exercise programs that can affect qol and fitness. Exercise programs can have various combinations of aerobic and resistance exercises. To make clinical practice recommendations, the Working Group of the Exercise for People with Cancer Guideline Development Group synthesized the evidentiary base. Research Questions ■ Does exercise, compared with no prescribed amount of exercise, improve domains of qol in patients with a diagnosis of cancer? Target Population

Cancer screening, prevention, and treatment in people with mental illness - Weinstein - 2015 - CA: A Cancer Journal for Clinicians Abstract Answer questions and earn CME/CNE People with mental illness die decades earlier in the United States compared with the general population. Most of this disparity is related to preventable and treatable chronic conditions, with many studies finding cancer as the second leading cause of death. Individual lifestyle factors, such as smoking or limited adherence to treatment, are often cited as highly significant issues in shaping risk among persons with mental illness. However, many contextual or systems-level factors exacerbate these individual factors and may fundamentally drive health disparities among people with mental illness. Introduction Mental Illness and Health Disparities Mental Illness and Cancer The evidence to date from epidemiologic studies regarding mental illness and cancer is now abundant, complex, and conflicting. Overall, studies of incidence vary widely along many dimensions. Theoretical Framework Materials and Methods Description of Search Strategy Individual level

Guidelines for perioperative care after radical cystectomy for bladder cancer: Enhanced Recovery After Surgery (ERAS®) society recommendations 8.Epidural analgesia (EDA) 9.Minimally invasive approach Minimally invasive pelvic surgery has been shown to decrease the inflammatory response when compared to the open approach. Laparoscopic rectal surgery seems to reduce the risk of postoperative ileus, complications and length of stay. However, long term oncological results are awaited before any higher LE statement can be drawn. Three prospective case series studies evaluated some form of minimally invasive approach to radical cystectomy. 10.Resection site drainage 11.Antimicrobial prophylaxis and skin preparation Regarding the optimal skin preparation, the ERAS recommendations in elective colorectal are of absolute value in cystectomy patients. 12.Standard anesthetic protocol Attention should be paid to maintain normoglycemia (possibly blood sugar less than 10 mmol/l), and adequate lung ventilation with low tidal volumes to limit peak airway pressure thus reducing the risk of barotrauma. 13.Perioperative fluid management

NCCN Task Force Report: Bone Health in Cancer Care Assessing Bone Health Osteoporosis and its associated increase in fracture risk is a major health issue for the aging population, and especially for patients with cancer. Hip and vertebral fractures are associated with chronic pain, decreased quality of life, and increased risk of death.1 Much of the morbidity and mortality associated with bone loss can be prevented with appropriate screening, lifestyle interventions, and therapy. Both cancer itself and cancer therapies can have profound effects on bone metabolism. These cancer therapy-related affects combine with other important clinical factors, such as age, prior fracture history, and family history of fracture, to further increase fracture risk.2,3 Lifestyle-related factors, such as smoking, excess alcohol intake, inadequate weight-bearing exercise, low calcium intake, and vitamin D deficiency, are common in patients with cancer. Bone Mineral Density The limitations of DXA measurement must also be recognized. The U.S. Fracture Risk

Diagnosis, assessment and management of constipation in advanced cancer: ESMO Clinical Practice Guidelines Skip to Main Content Sign In Register Close Advanced Search Online ISSN 1569-8041 Print ISSN 0923-7534 Copyright © 2018 European Society for Medical Oncology Connect Resources Explore Oxford University Press is a department of the University of Oxford. Close

Nutritional Screening Tools Used and Validated for Cancer Patients: A Systematic Review: Nutrition and Cancer: Vol 71, No 6 The purpose of this systematic review was to identify validated nutritional screening tools for cancer patients. The research was conducted in the electronic databases Pubmed, Cochrane Library, Scopus, and Biblioteca Virtual de Saúde (BVS), using the descriptors “Nutrition Assessment”, “Neoplasms”, and “Validation studies”. Initially, we identified 168 articles. Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer - Schmitz - - CA: A Cancer Journal for Clinicians Introduction Multiple US and international organizations have published exercise recommendations for patients living with and beyond cancer, including the American Cancer Society (ACS),1 the American College of Sports Medicine (ACSM),2 Exercise and Sports Science Australia,3 Cancer Care Ontario,4 and the Clinical Oncology Society of Australia.5 In March 2018, the ACSM convened a Second Roundtable on Exercise and Cancer Prevention and Control. This second Roundtable included 17 organizations from multiple disciplines (see Supporting Table 1) and set out to review and update prior recommendations on cancer prevention and control. The products of this Roundtable include 3 articles. The first article from the 2018 ACSM Roundtable presents the evidence that exercise is associated with a lower risk of developing cancer and improved survival after a cancer diagnosis.6 A summary of the evidence from this review and the other recent reviews on this topic7, 8 is provided in Table 1. Step 1: Assess

American College of Sports Medicine Roundtable Report on Phy... : Medicine & Science in Sports & Exercise It was estimated that 18.1 million individuals were diagnosed with cancer in 2018 and 9.6 million individuals died from the disease—making cancer the second leading cause of mortality worldwide (1). In the United States (US) alone, the lifetime risk of developing cancer is 40% in men and 38% in women (2), and 1.74 million individuals were diagnosed with cancer in 2018 (3). There are also high direct and indirect costs related to the cancer burden; for example, in the US alone, the annual cost of cancer care is US $158 billion (4), with billions of additional dollars lost to disability, lost work, and lost household productivity (5). Thus, the burden of cancer remains a significant public health issue worldwide, and there is an increasing need to understand how modifiable health behaviors like physical activity may help prevent and control cancer in the population. Cancer Types Associated with Physical Activity Type, Amount, Intensity, and Timing of Physical Activity Physical activity type

The Role of Nutritional Support for Cancer Patients in Palliative Care | HTML 1. Introduction The role of nutritional support for cancer patients in palliative care is still a controversial topic. Palliative care was established in the United Kingdom 50 years ago [4]. Timing is among the most important variables in identifying the indication for nutritional support in cancer patients in palliative care. The purpose of this narrative review is intended to be a brief guide to prescribing nutritional support based on the European Society for Clinical Nutrition and Metabolism (ESPEN) guidelines [9] and analysis of the literature evidence in palliative cancer patients. Figure 1. 2. According to Global Cancer Observatory (GLOBOCAN) estimates, about 18.1 million new cancer patients and 9.6 million cancer-related deaths occurred in 2018 worldwide. In recent years, patients with advanced cancer were defined as those with distant metastases, late-stage disease, and/or with prognosis of 6 to 24 months. Cancer is a systemic, complex, and heterogeneous disease. 3. 4. 5. 6.