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Obeticholic Acid Obeticholic Acid General Information : Obeticholic acid, is a semi-synthetic bile acid analogue which has the chemical structure 6α-ethyl-chenodeoxycholic acid. It is used as a drug to treat primary biliary cholangitis, and is undergoing development for several other liver diseases and related disorders.Approval is limited to monotherapy in patient's who are intolerant to ursodeoxycholic acid, or in combination with ursodeoxycholic acid in adults who have not responded adequately to ursodeoxyholic acid alone. 1 Obeticholic acid given orally, binds to the farnesoid X receptor (FXR), a receptor found in the nucleus of cells in the liver and intestine. FXR is a key regulator of bile acid metabolic pathways. Obeticholic acid increases bile flow from the liver and suppresses bile acid production in the liver, thus reducing the exposure of the liver to toxic levels of bile acids. Therapeutic Category – Obeticholic Acid is act as Gastrointestinal Agent. Product Characteristics: IUPAC Name:

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Daycare Services in Union City Benfotiamine General Information: Benfotiamine is a derivative of vitamin B1. It was developed in Japan specifically to treat Korsakoff's syndrome Benfotiamine reduces the extra biosynthesis and accumulation of a number of glucose metabolites, including glyceraldeyde-3-phosphate and dihydroxyacetone phosphate. Elevated levels of those glucose intermediates function as a trigger to most of the mechanisms accountable for hyperglycemia-caused cell damage. Benfotiamine increases tissue amounts of thiamine diphosphate, consequently growing transketolase activity and producing a significant decrease in glucose metabolites and precursors to AGEs. Up to now, two of the most effective AGE inhibitors in living microorganisms would be the Vitamin B1 derivative, benfotiamine and also the Vitamin B6 derivative, pyridoxamine. Therapeutic Category: Benfotiamine falls under the Anti –Biotic drugs category. Primary Characterstics: IUPAC Name: Molecular Formula: Molecular Weight: ‎466.449 g/mol Molecular Structure:

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Dirt bike riding victorian high Country Ride Calendar Dargo 2 day March 7-9 We're kicking off our tour calendar with 2 days of riding out of Dargo, Vic. We'll be riding some of the best tracks in the Victorian High Country across 2 days! Included in this event. - Camping at the Dargo River Inn for Saturday and Sunday night with access to showers and toilets - All meals provided - Day tour on Sunday and Monday with lunch, cold drinks, trail snacks, fuel and support vehicle provided Price per person: $450 Dinner and breakfast will be provided by the Dargo River Inn. PLEASE NOTE. Bookings must be made 7 days prior to the start of the event. dargo 2 day April 25-27 We're back in Dargo for our second event of the year! - Camping at the Dargo River Inn for Saturday and Sunday night Rawson, vic. 2 day June 6 - 8 This one is going to be a blast! Included in this event: - 2 nights accommodation, Saturday and Sunday, nights at the Mountain Rivers Tourist Park and meals provided by the Stockyard Pub Price per person: $560 dargo 2 day snow ride august 2

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