Hydroxychloroquine and azithromycin for coronavirus study – does not work Because of an awful study from France published on 20 March 2020, Donald Trump and other non-scientists pushed hydroxychloroquine and azithromycin for coronavirus. Of course, this old dinosaur and many others like Orac, who has written several articles about it, found the evidence that hydroxychloroquine, usually with the antibiotic azithromycin, had any effect on COVID-19 was very weak. But a small retrospective study showed hydroxychloroquine and azithromycin had no positive effect on the course or outcomes from severe cases of COVID-19. What is hydroxychloroquine? Chloroquine was approved in October 1949 for treating malaria, and it was the anti-malarial drug of choice for many years. Although it is no longer used as an anti-malarial, chloroquine and its derivative hydroxychloroquine have found a new life for the treatment of a number of other conditions. In addition, chloroquine is used to control the aquarium fish parasite Amyloodinium ocellatum, so many people have the drug nearby.
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1. - PubMed - NCBI Evidence Based Medicine – New Approaches and Challenges UW experts on novel coronavirus (COVID-19) The University of Washington is home to many experts on topics related to the COVID-19 pandemic. Expand each topic to see their names and specific expertise. Click on an expert’s name to view their contact information, recent media mentions and more. Public health Click on an expert’s name to view their contact information, recent media mentions and more. Medicine and virology For experts in the School of Medicine, please contact the UW Medicine Newsroom. Mental health and human connection Policy, law, political science and supply chain Business and economics Education Misinformation Environment We will be expanding this list on an ongoing basis. Recent COVID-19 news coverage
About Clinician Reviews | Clinician Reviews Clinician Reviews is written for NPs and PAs, by PAs and NPs, covering topics of vital interest to health care practitioners. Clinician Reviews reaches more than 125,000 PAs and NPs online and in print and has been serving our audience for more than 25 years. In 2019, Clinician Reviews won a silver award in the Best Use of Infographics category for our Third Annual Job Satisfaction Survey. This highly regarded honor from the American Society of Healthcare Publication Editors signals excellence in competition with the very best that the health care sector offers. The survey was fielded to more than 1,200 NPs and PAs, and the resulting data was presented as engaging infographics. Mission Statement Clinician Reviews is a monthly, peer-reviewed publication dedicated to keeping the ever-growing nurse practitioner and physician assistant professions up-to-date on the latest advances in medicine and health care news. Editor Karen J. kclemments@mdedge.com Managing Editor Ann M. ahoppel@mdedge.com
9 Amazing Facts about Musculoskeletal Ultrasound Imaging Ultrasound used in Athletics Are you a coaching an athlete complaining about a training injury they cannot run through? Have you often been frustrated as a coach or athlete about the general lack of medical support in your sport? Are you a strength coach designing a program for an injured athlete with no exact diagnosis? I have often heard coaches in many sports who are frustrated with designing programs around injuries that remain unresolved and are still painful despite months of “rest and ice”. Musculoskeletal Ultrasound (MSUS) is quickly becoming the imaging test of choice for Sports Medicine doctors working with high performance athletes who need to obtain a quick and accurate diagnosis. Non-traumatic sports injuries often occur at the musculotendonous junction, which is considered the weakest portion of the muscle-tendon complex. Did you know MSUS can see old tendonosis or tendonopathies? What about ligament sprains? How come you have haven’t heard about it before? What is the solution?
UW researchers respond to novel coronavirus (COVID-19) COVID-19 experts for reporters US coronavirus predictions are shifting — here’s why Things are still getting worse. Source: CNN Here are the most recent stories of UW experts commenting on the novel coronavirus epidemic In addition to UW researchers from a variety of disciplines offering their expertise to journalists covering the novel coronavirus, UW Medicine researchers are leading the way in the detection and prevention of COVID-19 and other coronaviruses. This page is updated every week day. Some of the stories below may require a third-party subscription. More 2018 | Electronic Nose Analyses Breath to Diagnose Disease In Brief Researchers are building an electronic nose that can accurately detect and distinguish chemicals in your breath, which could lead to earlier diagnosis of diseases and eventually replace blood tests. Beta testing is targeted early in 2018. A Breath Test In Place of Blood Test A team of researchers from the Texas Analog Center of Excellence (TxACE) at UT Dallas are working on a device that can analyze your breath and diagnose a wide range of diseases, called an “electronic nose.” “Smell is one of the senses of humans and animals, and there have been many efforts to build an electronic nose,” said Dr. The rotational spectrometer can detect low levels of chemicals in the breath using electromagnetic waves, which it transmits over a wide range of frequencies. Notably, this is effective for disease detection because gases that come out in breath contain information about practically every part of the body. More Affordable, And Hopefully Portable
Stakeholder expectations from the integration of chiropractic care into a rehabilitation setting: a qualitative study | BMC Complementary and Alternative Medicine | Full Text This qualitative study offers new insights into stakeholder expectations from the integration of chiropractic services into inpatient healthcare facilities, such as the rehabilitation specialty hospital that served as the setting for this research. Despite this being a unique setting for the addition of chiropractic care, research on chiropractic integration into different hospital settings in Canada and the US has demonstrated very similar themes [16, 25]. Patients, families, and providers affirmed the notion that the chiropractor’s overall contribution to the healthcare team was to support rehabilitation patients in their quests of making progress toward discharge to the community. Within this framework, stakeholders expected that the chiropractors’ primary focus would be on pain management, with clinically demonstrative functional improvements another likely outcome. Limitations
No, COVID-19 Is Not Like The Flu—And We Have To Stop Comparing Them | The Well by Northwell I don’t know why everyone is freaking out. The flu kills tens of thousands of people each year, and no one is shutting down borders because of that. Sound familiar? It’s a common refrain from the past few weeks as the novel coronavirus, also known as COVID-19, made its way across borders from Wuhan, China. It’s something I (now shamefully) admit to saying, myself, when this all first started. And the confusion is understandable. “We are familiar with coronaviruses because, for a long time now, strains of coronavirus have circulated in our community and caused respiratory illnesses such as ‘the common cold’. Here’s what we do know: It’s more deadly—and much more contagious. Though we won’t know the actual death rate until COVID-19 is contained and under control, we do know that it’s proving to have a higher death toll—or, in epidemiological terms, “case fatality rate.” And though the elderly are the hardest hit by this virus, they aren’t the only ones at risk. We don’t have immunity.
Enhancing implementation science by applying best principles of systems science | Health Research Policy and Systems | Full Text This review is grounded in the ongoing experiences of the authors to devise and implement interventions to promote health equity, including for older adults. Because the aforementioned interventions are both multilevel and dynamic, the scientific approaches employed evolved from utilising ecological models for thinking through pathways whereby determinants at the societal, community and interpersonal levels affect population and individual health and well-being [1–4], to embracing a portfolio of systems science models that usefully inform related research, practice, policy and education initiatives [5–7]. Forrester, the founder of system dynamics, famously explained that a manager’s verbal description of a corporate organisation constitutes a model [8]. Such mental models of corporations are used by managers to deal with problems that arise on a daily basis. They are not, however, the real corporation.
miofascial Releaser – Herramienta para instrument-assisted fascial Movilización – para los especialistas de deportes Medecine: Health & Personal Care Coronavirus mutations and vaccines – worse than murder hornets I am skeptical of the wild claims about getting a COVID-19 vaccine in 12-18 months, and now there is powerful research about coronavirus mutations that makes me very concerned about getting an effective vaccine. And you thought murder hornets were bad? These coronavirus mutations could mean a disaster for current vaccine research – if we’re developing vaccines for a previous strain of COVID-19, rather than more current (and apparently, more virulent) coronavirus vaccines. This makes the murder hornets look like a ladybug. A recent paper looks at a particularly dangerous strain of coronavirus mutations that should make us reassess any optimism about getting a new COVID-19 vaccine. Coronavirus mutations study Because of the urgency to get coronavirus research out for researchers, many papers are being published online as “preprints,” while they are being peer-reviewed by major journals. Dr. Dr. What this means for vaccines And remember, this is just the first mutation. Notes Citations Related
How an outsider bucked prevailing Alzheimer's theory, clawed for validation Robert Moir was damned if he did and damned if he didn’t. The Massachusetts General Hospital neurobiologist had applied for government funding for his Alzheimer’s disease research and received wildly disparate comments from the scientists tapped to assess his proposal’s merits. It was an “unorthodox hypothesis” that might “fill flagrant knowledge gaps,” wrote one reviewer, but another said the planned work might add little “to what is currently known.” A third complained that although Moir wanted to study whether microbes might be involved in causing Alzheimer’s, no one had proved that was the case. As if scientists are supposed to study only what’s already known, an exasperated Moir thought when he read the reviews two years ago. He’d just had a paper published in a leading journal, providing strong data for his idea that beta-amyloid, a hallmark of Alzheimer’s disease, might be a response to microbes in the brain. But something had long bothered him about the “evil amyloid” dogma. Dr.
Exploring issues and controversies in the relationship between science and medicine by williamweyer Feb 6